Lecture 1 - History of Neuroscience - Introduction - Part 1
Lecture 2 - History of Neuroscience - Introduction - Part 2
Lecture 3 - Factors that produce discoveries
Lecture 4 - Importance of the 1950s in Neuroscience
Lecture 5 - Advances in Molecular Biology (Genes to DNA)
Lecture 6 - Discovery of the structure of the DNA
Lecture 7 - How DNA works
Lecture 8 - Molecular biology of the human brain
Lecture 9 - Signaling molecule: The First growth Factor
Lecture 10 - Nerve Growth Factor
Lecture 11 - Organizing the Connections
Lecture 12 - Axonal Transport
Lecture 13 - Signaling molecules: The First Neurotransmitter in the brain
Lecture 14 - The concept of Lock and Key
Lecture 15 - The Soup vs Sparks Debate
Lecture 16 - Intracellular Electrode, Neurotransmitter in the Brain, Dales Law
Lecture 17 - Early evidence of Acetylcholine and Glutamate
Lecture 18 - Early evidence of GABA and Serotonin
Lecture 19 - Catecholamine and Hormones
Lecture 20 - Second messengers and Hormones
Lecture 21 - Pheromones
Lecture 22 - Revolution in Cytology
Lecture 23 - Synapse and the 'Neuronism vs Reticularism' debate
Lecture 24 - Contributions by Rene Couteaux and George Koelle
Lecture 25 - Chemical Synapse
Lecture 26 - Synapse and the Neuromuscular Junction
Lecture 27 - The Electrical Synapse and Myelin
Lecture 28 - Physiology: The Action Potential - Part 1
Lecture 29 - Recording nerve impulses and single action potentials
Lecture 30 - Recording from nerve and plant cells
Lecture 31 - Recording Local circuits, Hodgkin and Huxely contributions - Part 1
Lecture 32 - Hodgkin and Huxely model - Part 2 and Kenneth Cole Contributions
Lecture 33 - GHK equation and HH action potentials
Lecture 34 - First Electrophysiological Evidence for Synaptic Transmission
Lecture 35 - Bernard Katz
Lecture 36 - End-Plate Potential and Synaptic Quanta
Lecture 37 - Eccles and Spinal motor neuron
Lecture 38 - Invertebrate simple systems: Aplysia
Lecture 39 - Other studies of sensory responses
Lecture 40 - Legacy of Golgi and Ramo`n y Cajal
Lecture 41 - Dynamic polarization of Neuron
Lecture 42 - Modern Research
Lecture 43 - Synaptic Integration and Action Potential Initiation
Lecture 44 - Active properties of dendrites
Lecture 45 - Dendritic dominance
Lecture 46 - Dendritic spines
Lecture 47 - Rethinking the concept of Neuron Doctrine
Lecture 48 - Muscle spindles
Lecture 49 - Spinal cord pathways
Lecture 50 - Retinal Processing
Lecture 51 - Keffler Hartline
Lecture 52 - Stephen Kuffler and Horace Barlow
Lecture 53 - Expansion of the Reflex concept
Lecture 54 - Central Pattern generators
Lecture 55 - The cortical column
Lecture 56 - Vernon Mountcastle
Lecture 57 - Central Visual Processing
Lecture 58 - Central Visual Processing and Feature Detectors
Lecture 59 - Intracellular recordings from the brain - Part 1
Lecture 60 - Intracellular recordings from the brain - Part 2
Lecture 61 - Two motor systems
Lecture 62 - Auditory cortex and The pattern theory of olfaction
Lecture 63 - Arousal and Reticular activating system
Lecture 64 - Sleep and Rapid Eye Movements
Lecture 65 - Operant Conditioning by brain stimulation
Lecture 66 - Hypothalamus and Feeding Behavior
Lecture 67 - Brain as a gland
Lecture 68 - Hypothalamic-Neurohypophyseal System
Lecture 69 - Hypothalamic-Adenohypophyseal System
Lecture 70 - Founding Modern Neuroanatomy
Lecture 71 - Psychology and Ethology
Lecture 72 - Karl Lashley
Lecture 73 - Donald Hebb
Lecture 74 - Limbic system-Limbic Lobe and Papez Circuit
Lecture 75 - Limbic system-Kluver-Bucy Syndrome
Lecture 76 - The Limbic system and Amygdala
Lecture 77 - The Hippocampus and Patient H.M
Lecture 78 - Brenda Milner
Lecture 79 - Neurology: Foundations of Brain Imaging
Lecture 80 - The Neurological unit of the Boston City Hospital
Lecture 81 - Derek Denny-Brown, Raymond Adams and C. Miller Fisher
Lecture 82 - Montreal Neurological Institute
Lecture 83 - Cerebral Circulation
Lecture 84 - Spreading depression of Leo and Migraine
Lecture 85 - The Eradication of Polio
Lecture 86 - Origin of Neurosurgery
Lecture 87 - Harvey Cushing
Lecture 88 - Pituitary Surgery
Lecture 89 - Stereotaxy
Lecture 90 - Epilepsy
Lecture 91 - Psychosurgery
Lecture 92 - Antipsychotic Drugs
Lecture 93 - Reserpine
Lecture 94 - Monoamine Oxidase Inhibitors
Lecture 95 - Lithium
Lecture 96 - Benzodiazepines
Lecture 97 - Stress
Lecture 98 - Theoretical Neuroscience: Brain as computer and Computer as Brain
Lecture 99 - John Atanasoff
Lecture 100 - John von Newmann
Lecture 101 - Game and Information theory
Lecture 102 - Cybernetics and Artificial Intelligence
Lecture 103 - Towards Networks of Realistic Neurons: von Newman's Last word
Lecture 104 - Santiago Ramon y Cajal, 'The Peasant Genius'
Lecture 105 - 'Cajal- a giant wakes up'
Lecture 106 - Cajal's modifications to the Golgi method and studies of embryos and various systems
Lecture 107 - Law of dynamic polarization, support from others studies
Lecture 108 - Santiago Ramon y Cajal - Career turning point and Palm Sunday years
Lecture 109 - Cajal’s trailblazing discoveries that earned him the Nobel Prize
Lecture 110 - 'Enduring Legacy of Cajal'
Lecture 111 - Robert Barany - Early life and prior work done by other scientists
Lecture 112 - Robert Barany - The serendipitous discovery of the caloric test
Lecture 113 - Robert Barany - Vestibular System and connection to Cerebellum
Lecture 114 - Robert Barany - Modern Applications of Barany's work - Space medicine and Astronaut training
Lecture 115 - Robert Barany - Summary of Contributions
Lecture 116 - Charles Sherrington Personal Background
Lecture 117 - Charles Sherrington - quiet mind expt, Neuroplasiticity, animal locomotion studies
Lecture 118 - Charles Sherrington - Reciprocal innervation, Pain and Emotion, Mind and Body
Lecture 119 - Charles Sherrington's Magnum Opus - The integrative action of the nervous system
Lecture 120 - Charles Sherrington - Insights into life and work by Molnar and Brown
Lecture 121 - Charles Sherrington - Summary of contributions
Lecture 122 - Edgar Adrian, Keith Lucas and Novel instruments used in Neurophysiology
Lecture 123 - Edgar Adrian - Early life, All or none principle in neurons, Key findings with Keith Lucas
Lecture 124 - Edgar Adrian - Work with Alexander Forbes, Gasser and Erlanger (St. Louis connection)
Lecture 125 - Edgar Adrian - 'Failed experiment', Perseverance in science
Lecture 126 - Edgar Adrian - Recording from single sensory and motor neurons
Lecture 127 - Edgar Adrian - Nobel Prize, Admin work, Legacy
Lecture 128 - Edgar Adrian - Adventures with EEG
Lecture 129 - Edgar Adrian - Mapping cerebellar cortex, Cerebral cortex, Brain and Behavior, Olfaction
Lecture 130 - Hodgkin and Huxley - Biographical background, Scientific backdrop and state of Neurophysiology
Lecture 131 - Hodgkin and Huxley - Meeting of great minds and Challenges faced - Part 1
Lecture 132 - Hodgkin and Huxley - Meeting of great minds and Challenges faced - Part 2
Lecture 133 - Bernard Katz - personal background, scientific backdrop, soup vs spark debate
Lecture 134 - Bernard Katz - Quantal nature of synaptic transmission, Vesicle hypothesis, foundational work
Lecture 135 - Bernard Katz - del Castillo model of receptor activation, role of calcium in synapses, sodium
Lecture 136 - Bernard Katz Paper: The fine structure of neuromuscular junction of the frog
Lecture 137 - Roger Sperry - Personal Background, Split brain patients, Hemispheric specialization
Lecture 138 - Roger Sperry: Split Brain patients and Dichotomous consciousness
Lecture 139 - Roger Sperry: Unified consciousness and Behavioural differences in split brain patients,
Lecture 140 - Roger Sperry, Gazzaniga's Interpreter theory, Impact on Psychology and Neuroscience, Nobel Prize
Lecture 141 - Roger Sperry's Chemoaffinity hypothesis paper
Lecture 142 - Roger Sperry paper 'Mentalism: Yes, Dualism:No'
Lecture 143 - Jens Christian Skou Part 1 : The Story of Jens Christian Skou's life in science
Lecture 144 - Jens Christian Skou: Sodium Potassium pump overview and Nobel Prize
Lecture 145 - Jens Christian Skou: Paper - 'The Influence of Some Cations on an Adenosine Triphosphate
Lecture 146 - Arvid Carlsson - Personal Background, Education and Early Career, Pivot, Nobel prize contributions
Lecture 147 - Arvid Carlsson - History of L Dopa
Lecture 148 - Arvid Carlsson - Antipsychotics, Dopamine hypothesis, Serotonin and SSRIs, Omeprazole
Lecture 149 - Eric Kandel - Early life and nobel prize winning work
Lecture 150 - Eric Kandel - Synaptic Plasticity
Lecture 151 - Eric Kandel - Aplysia work, Short and long term memory and mechanisms
Lecture 152 - Paul Greengard - The Phosphorylation Paradigm
Lecture 153 - David Hubel and Torsten Wiesel - early life, education and collaboration
Lecture 154 - Hubel and Wiesel - Effect of early visual deprivation on cortical function
Lecture 155 - Hubel and Wiesel - Effect of visual misalignment on binocular integration
Lecture 156 - Hubel and Wiesel - Limited capacity for recovery following early visual deprivation